Shahrokh Makvand Hosseini
Semnan University, Iran
Title: Lithium and Bilirubin serum level changes in Bipolar 1 disorder patients using the complementary therapies of individual and family psycho-education: A randomized controlled trial design
Biography
Biography: Shahrokh Makvand Hosseini
Abstract
Objective: Complementary therapies such as psycho-education have been much considered by therapy society of bipolar patients. This study aims to investigate the effects of complementary therapies of individual and family psychoeducation besides drug adherence of the bipolar I patients in improvement of two crucial biomarkers of Lithium and Bilirubin.Method: After checking the inclusion- exclusion criteria, a sample of 66 patients with bipolar disorder I were purposively selected and randomly divided into three groups: individual psycho- education, family psycho-education and control group (isolated medication therapy). Lithium and Bilirubin serum levels were then measured using the Pars Azmoon laboratory kits in pretest, posttest and follow-up stages.Findings: Data were extracted using the laboratory tests and analyzed by a GLM: Multivariate Analysis of Covariance. Results were shown a significant difference in the Lithium level for the research groups. Family psychoeducation subjects with drug adherence in the posttest and follow up stages were showed significantly higher average compared to control group in terms of Lithium serum level, whereas no significant effect was observed for individual psychoeducation. No significant effects were also found for bilirubin serum level.Conclusion: The family psychoeducation beside psychiatric treatment of bipolar I patients could effectively increase the Lithium serum level and is then recommended to clinicians in the treatment of these patients.