Gino Serra
Universita di Sassari, Italy
Biography
Gino Serra is a Psychiatrist and Full Professor of Pharmacology at the University of Sassari, Department of Biomedical Science. In 1979 he first suggested that potentiation of dopaminergic transmission in neurons arising in the substantia nigra/ventral-tegmental-area induced by repeated treatment with antidepressants plays an important role in their therapeutic effects Recently, He suggested , and he and his collaborators developed preliminary clinical support for the proposal that memantine may exert beneficial, mood-stabilizing effects. Indeed, they have recently observed in 3 naturalistic clinical studies that memantine, as an augmenting agent, was associated with clinically substantial antimanic and sustained mood-stabilizing effects in otherwise treatment-resistant bipolar disorder patients, with excellent tolerability and safety.
Abstract
Abstract : Memantine: A new mood-stabilizer for treatment-resistant Bipolar disorders